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Cover Letter 
Dear Editor of the Brazilian Journal of Physical Therapy (BJPT), 
• The objective and approach of your research 
The heterogeneity of information known so far has not yet allowed making concise 
recommendations and protocols for the elaboration of a physical exercise (PE) program 
for patients with Kidney Failure (ESRD), especially among those undergoing 
hemodialysis (HD). Thus, this study aims to perform a literature review on the effect of 
PE on patients with kidney failure, describing its protocols and clinical outcomes in order 
to guide future interventions for this population. 
• Any novel contributions reported 
In conclusion, the survey of information indicates lack of standardization of protocols that 
specify the PE training modality, moment, frequency, duration and intensity. Most articles 
reported PE during the HD session through aerobic PE with average duration of 30 
minutes, the most common being three times a week, medium to high intensity and 
prevalence of 12 weeks, mostly supervised by health professionals. Thus, further studies 
and the development of PE protocols are suggested to achieve optimal efficacy for this 
population and, as this is a subject still little explored, studies addressing intervention 
with interdialysis physical exercise are needed. In general, the evidence gathered in this 
systematic review suggests that PE is beneficial and safe for patients with ESRD. 
• Why your manuscript should be published in this journal 
Considering the low levels of PE as possible risk factors that affect the prognosis of 
patients with ESRD on hemodialysis, knowledge and prevention of these conditions are 
important to improve the management of the disease and the quality of life of these 
individuals. Furthermore, the findings of our study may help guide healthcare 
professionals in decision-making, recommendations, and development guidelines 
regarding the PA program that may help reduce the adverse risk of ESRD both the 
individual and the population level. 
 
 
 
 
 
• Related papers by you and/or your fellow authors (published or under 
consideration) 
Knob AM, Oliveira MTJ, Freitag AF. O efeito de uma sessão de treino em pacientes com 
doença renal crônica. LECTURAS EDUCACIÓN FÍSICA Y DEPORTES, v. 27, p. 201-
214, 2023. DOI: https://doi.org/10.46642/efd.v27i297.3497 
Freitag AF, Oliveira MTK, Marchini KB. Prescrição de Exercício Físico para o Idoso com 
Doença Renal Crônica. Educação Física em GERONTOLOGIA. 1ed.Curitiba-PR: 
Appris, 2021, v. 01, p. 225-235. ISBN: 9786525004822 
• No previous reviews of our submission 
• No previous submissions of our manuscript to that journal 
• Previous communication you’ve had with journal staff 
The previous communication that I had with journal staff was via e-mail, to have some 
information about. 
• Considerations 
 Thus, we submit for your appreciation the scientific text entitled “EFFECT OF 
PHYSICAL EXERCISE ON PATIENTS WITH RENAL FAILURE: A SYSTEMATIC 
REVIEW”, which fits the areas of interest of BJSM. The magazine was chosen for 
addressing issues related to PE and health. 
 All authors declare to be aware that the study, after being submitted, cannot have 
the order or number of authors changed, without prior information and justification to the 
BJSM and, also, that they contributed to the development of this research and its writing, 
as well as approved your content prior to submission. 
 The authors certify that this scientific text is not characterized as multipart and/or 
partial results of the same study and represents original research. 
 The authors also declare that there is no conflict of interest in relation to this 
scientific text. 
Maringá-Paraná-Brazil, 03/02/2023 
 
 
___________________ 
Abel Felipe Freitag 
Corresponding author 
https://doi.org/10.46642/efd.v27i297.3497